Introduction

As of mid-2025, the Thermo set of External tools downloaded under the name PRM Conductor includes 5 different tools

• GPF Creator
  • an small application that automates the creation of multiple instrument method DIA files to span a precursor range for a gas-phase-fractionation experiment
• GPF Importer
  • a small application that automates the import of GPF or any peptide search data from Proteome Discoverer. This program imports the data with defaults that are appropriate for the Stellar MS, but the same result can be achieved through the Skyline File / Import / Peptide Search wizard.
• PRM Conductor
  • an application that aids in the creation of targeted MS methods. This program filters "bad" transitions, and selects "good" peptides via a set of criteria, and helps the user to create one or more instrument methods that will be acquired with at least a required number of points per peak.
• Expert Review
  • an application that helps achieve consistent peak integration boundaries, through the use of replicate-level and experiment level correlations to reference data of various types.
• Sequence Import Configure
  • a tiny application that saves a file on the instrument computer, which allows to automatically import .raw files into a Skyline file after the .raw file acquisition is finished