Welcome to the LINCS PCCSE!

2019-11-17

WELCOME TO THE LINCS PCCSE PANORAMA REPOSITORY

This is the LINCS Proteomic Characterization Center for Signaling and Epigenetics (PCCSE) Panorama Repository for the reduced representation phosphoproteomics assay ("P100") and global chromatin profiling assay ("GCP") primary mass chromatogram data. Our center makes systematic perturbations (drug treatments, gene disruption/editing, and directed differentiation) in a variety of biological models including cancer and neurodevelopment. We read out molecular changes in the cells in the spaces of phosphosignaling (P100) and histone modification (GCP). In collaboration with the LINCS Center for Transcriptomics, we also read out changes in transcription using their L1000 assay. Look here for more information about our center or download our poster here.

PCCSE EXPERIMENTAL PARADIGMSANNOUNCING THE PCCSE PROTEOMICS CONNECTIVITY HUB
PCCSE Data Generation ParadigmsCLUE Proteomics Hub

Go beyond the heatmaps!  Explore connections and relationships among our perturbations in the Proteomics Connectivity Hub, a collaboration with the Connectivity Map Project.  Free account creation required.

NEW! ASMS 2017 Poster from our group!