UCLA Loo Lab - bone marrow PRM

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Measurement of Nrf2-Regulated Antioxidant Response Proteins as Potential Biomarkers for Radiation Injury Assessment

  • Organism: Mus musculus
  • Instrument: Q Exactive
  • SpikeIn: Yes
  • Keywords: radiation, biomarker, parallel reaction monitoring
Using targeted mass spectrometry, we examined the response of Nrf2-ARE-dependent enzymes in mouse bone marrow collected at various time points (8 hours to 4 days) after 6 Gy total body irradiation in two mouse strains and both genders. Relative protein abundances and statistical significance compared to unirradiated control mice were analyzed in Skyline and MSstats.
Created on 1/15/19, 10:21 PM