Quality Control 2

This folder contains QC data acquired by Michael Bereman's lab at NCSU, and published in the Journal of Proteome Research.

An Automated Pipeline to Monitor System Performance in Liquid Chromatography Tandem Mass Spectrometry Proteomic Experiments Michael S. Bereman, Joshua Beri, Vagisha Sharma, Cory Nathe, Josh Eckels, Brendan MacLean, Michael J. MacCoss. Journal of Proteome Research. 2016
[abstract] [pdf]


The QC data was collected over a period of three years by the Bereman lab at NC State University.  We have used this data to monitor various aspects of instrument performance on our Q-Exactive plus instrument, including:

  • General instrument performance, including LC and MS system suitability (mass measurement accuracy and LC retention time, peak area, etc.).
  • Evaluation of new technology (3 um C18 packed nLC column vs. 1.9 um C18 packed UHPLC column).
  • Trends in long-term instrument performance (monitoring of precursor/transition peak area ratio).

Dates of data used for figures in the paper are as follows:

Fig. 2: 2016-05-09 to 2016-06-28

Fig. 3: 2016-02-03 to 2016-02-29

Fig. 4: 2015-06-30 to 2016-02-19

Fig. 5: 2014-08-27 to 2016-05-31