Figure 5 Distance dependence of successive errors

(B)   Distance dependence of error cluster formation. Left panel: Distance dependence Ef(next)  for Apr, Par and Str. Data from Figures 4A,D, 5A, S7A, and S8. The probability for error cluster formation are normalized to that of Str value, which is almost not distance-dependent and is set to 1 (Methods). Error bars represent the standard deviation of the mean between different error clusters. The number of cluster are indicated in the circles. Middle and right panel: Distance dependence of error cluster formation for different AGA based on PRM measurements. Each point represents a mean value of up to three error clusters.

(C)   Correlation between Ef(first) and Ef(next)  for different AGAs. Data are from (B). Only clusters with adjacent substitutions are considered (F47L-D48E; E241D-E242D). Color code as in Figure 5B.