Signal from different sample batches, different acquisition methods, different instrument platforms, or different laboratory sites is not inherently calibrated. Although the "true" quantity (x axis) of one sample measured on one instrument may be more than the quantity of another sample measured on another instrument, the raw chromatogram peak areas may not reflect these differences because the signals are not calibrated. By placing the signal (or two sample batches, or two laboratories) on the same scale, measurements are harmonized across these different data sets.

On this page you'll find the raw acquisition files and the processed Skyline documents. For processed data matrices and code to regenerate figures, please see our Bitbucket page: https://bitbucket.org/lkpino/single-point_calibration/wiki/Home