sp|P0000|Aducanumab: /Indiana U - Proteome Analysis/Reproducability and repeatability Aducanumab Assay/Peptide Modification Testing (CAA and Ox)

Protein

File	Aducanumab_digestion_ratio_test_spikein_2025-02-26_14-39-46.sky.zip 242 MB SkyP file (link only, 1KB) Full Skyline file Copy relative URL to clipboard Copy full URL to clipboard
Description	Chimeric Heavy
Decoy	false
Accession	P0000
Note	Adu_heavy

Sequence Coverage

View Settings

By: Replicate: Modified forms: Combined Stacked

The number displayed on each peptide box is the rank
1										11										21										31										41										51										61										71										81										91
Q	V	Q	L	V	E	S	G	G	G	V	V	Q	P	G	R	S	L	R	L	S	C	A	A	S	G	F	A	F	S	S	Y	G	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	V	A	V	I	W	F	D	G	T	K	K	Y	Y	T	D	S	V	K	G	R	F	T	I	S	R	D	N	S	K	N	T	L	Y	L	Q	M	N	T	L	R	A	E	D	T	A	V	Y	Y	C	A	R	D	R
																																																																																							1

101										111										121										131										141										151										161										171										181										191
G	I	G	A	R	R	G	P	Y	Y	M	D	V	W	G	K	G	T	T	V	T	V	S	S	A	K	T	T	A	P	S	V	Y	P	L	A	P	V	C	G	D	T	T	G	S	S	V	T	L	G	C	L	V	K	G	Y	F	P	E	P	V	T	L	T	W	N	S	G	S	L	S	S	G	V	H	T	F	P	A	V	L	Q	S	D	L	Y	T	L	S	S	S	V	T	V	T	S	S	T	W	P


201										211										221										231										241										251										261										271										281										291
S	Q	S	I	T	C	N	V	A	H	P	A	S	S	T	K	V	D	K	K	I	E	P	R	G	P	T	I	K	P	C	P	P	C	K	C	P	A	P	N	L	L	G	G	P	S	V	F	I	F	P	P	K	I	K	D	V	L	M	I	S	L	S	P	I	V	T	C	V	V	V	D	V	S	E	D	D	P	D	V	Q	I	S	W	F	V	N	N	V	E	V	H	T	A	Q	T	Q	T	H	R


301										311										321										331										341										351										361										371										381										391
E	D	Y	N	S	T	L	R	V	V	S	A	L	P	I	Q	H	Q	D	W	M	S	G	K	E	F	K	C	K	V	N	N	K	D	L	P	A	P	I	E	R	T	I	S	K	P	K	G	S	V	R	A	P	Q	V	Y	V	L	P	P	P	E	E	E	M	T	K	K	Q	V	T	L	T	C	M	V	T	D	F	M	P	E	D	I	Y	V	E	W	T	N	N	G	K	T	E	L	N	Y	K	N


401										411										421										431										441										451
T	E	P	V	L	D	S	D	G	S	Y	F	M	Y	S	K	L	R	V	E	K	K	N	W	V	E	R	N	S	Y	S	C	S	V	V	H	E	G	L	H	N	H	H	T	T	K	S	F	S	R	T	P	G

Annotations for sp|P0000|Aducanumab

Description	Chimeric Heavy
Gene name
Organism	Unknown unknown

Genbank IDs	GIs	Swiss-Prot Accessions	Swiss-Prot Names	Ensembl	IPI Numbers	GO Categories
none loaded	none loaded	none loaded	none loaded	none loaded	none loaded	none loaded

Peptides

Select All Select None Show Selected Show Unselected Show All	Peptide Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Bar Chart Pie Chart Quick Chart	Peptide Neutral Mass Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart	Missed Cleavages Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart	Avg. Measured RT Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart	Predicted RT Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart	RT Score Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart
Select All Select None Show Selected Show Unselected Show All	Peptide Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Bar Chart Pie Chart Quick Chart	Peptide Neutral Mass Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart	Missed Cleavages Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart	Avg. Measured RT Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart	Predicted RT Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart	RT Score Sort Ascending Sort Descending Clear Sort Filter... Clear Filter Remove Column Summary Statistics... Box & Whisker Quick Chart
	AEDTAVYYCAR	1317.5660	0	4.0759

Chromatograms

Display Chart Settings

█ AEDTAVYYC[+57.021464]AR

Summary Charts

Replicate:

CV Values:

Log Scale:

Width:

Height:

Value:

Value only effects Retention Times chart.

PanoramaWeb

PanoramaWeb

sp|P0000|Aducanumab

Protein

Sequence Coverage

View Settings

Annotations for sp|P0000|Aducanumab

Peptides

Chromatograms

Replicate Filters

Annotation Filters

Summary Charts

Peak Areas

Retention Times

1										11										21										31										41										51										61										71										81										91
Q	V	Q	L	V	E	S	G	G	G	V	V	Q	P	G	R	S	L	R	L	S	C	A	A	S	G	F	A	F	S	S	Y	G	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	V	A	V	I	W	F	D	G	T	K	K	Y	Y	T	D	S	V	K	G	R	F	T	I	S	R	D	N	S	K	N	T	L	Y	L	Q	M	N	T	L	R	A	E	D	T	A	V	Y	Y	C	A	R	D	R
																																																																																							1

101										111										121										131										141										151										161										171										181										191
G	I	G	A	R	R	G	P	Y	Y	M	D	V	W	G	K	G	T	T	V	T	V	S	S	A	K	T	T	A	P	S	V	Y	P	L	A	P	V	C	G	D	T	T	G	S	S	V	T	L	G	C	L	V	K	G	Y	F	P	E	P	V	T	L	T	W	N	S	G	S	L	S	S	G	V	H	T	F	P	A	V	L	Q	S	D	L	Y	T	L	S	S	S	V	T	V	T	S	S	T	W	P


201										211										221										231										241										251										261										271										281										291
S	Q	S	I	T	C	N	V	A	H	P	A	S	S	T	K	V	D	K	K	I	E	P	R	G	P	T	I	K	P	C	P	P	C	K	C	P	A	P	N	L	L	G	G	P	S	V	F	I	F	P	P	K	I	K	D	V	L	M	I	S	L	S	P	I	V	T	C	V	V	V	D	V	S	E	D	D	P	D	V	Q	I	S	W	F	V	N	N	V	E	V	H	T	A	Q	T	Q	T	H	R


301										311										321										331										341										351										361										371										381										391
E	D	Y	N	S	T	L	R	V	V	S	A	L	P	I	Q	H	Q	D	W	M	S	G	K	E	F	K	C	K	V	N	N	K	D	L	P	A	P	I	E	R	T	I	S	K	P	K	G	S	V	R	A	P	Q	V	Y	V	L	P	P	P	E	E	E	M	T	K	K	Q	V	T	L	T	C	M	V	T	D	F	M	P	E	D	I	Y	V	E	W	T	N	N	G	K	T	E	L	N	Y	K	N


401										411										421										431										441										451
T	E	P	V	L	D	S	D	G	S	Y	F	M	Y	S	K	L	R	V	E	K	K	N	W	V	E	R	N	S	Y	S	C	S	V	V	H	E	G	L	H	N	H	H	T	T	K	S	F	S	R	T	P	G

1										11										21										31										41										51										61										71										81										91
Q	V	Q	L	V	E	S	G	G	G	V	V	Q	P	G	R	S	L	R	L	S	C	A	A	S	G	F	A	F	S	S	Y	G	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	V	A	V	I	W	F	D	G	T	K	K	Y	Y	T	D	S	V	K	G	R	F	T	I	S	R	D	N	S	K	N	T	L	Y	L	Q	M	N	T	L	R	A	E	D	T	A	V	Y	Y	C	A	R	D	R
																																																																																							1

101										111										121										131										141										151										161										171										181										191
G	I	G	A	R	R	G	P	Y	Y	M	D	V	W	G	K	G	T	T	V	T	V	S	S	A	K	T	T	A	P	S	V	Y	P	L	A	P	V	C	G	D	T	T	G	S	S	V	T	L	G	C	L	V	K	G	Y	F	P	E	P	V	T	L	T	W	N	S	G	S	L	S	S	G	V	H	T	F	P	A	V	L	Q	S	D	L	Y	T	L	S	S	S	V	T	V	T	S	S	T	W	P


201										211										221										231										241										251										261										271										281										291
S	Q	S	I	T	C	N	V	A	H	P	A	S	S	T	K	V	D	K	K	I	E	P	R	G	P	T	I	K	P	C	P	P	C	K	C	P	A	P	N	L	L	G	G	P	S	V	F	I	F	P	P	K	I	K	D	V	L	M	I	S	L	S	P	I	V	T	C	V	V	V	D	V	S	E	D	D	P	D	V	Q	I	S	W	F	V	N	N	V	E	V	H	T	A	Q	T	Q	T	H	R


301										311										321										331										341										351										361										371										381										391
E	D	Y	N	S	T	L	R	V	V	S	A	L	P	I	Q	H	Q	D	W	M	S	G	K	E	F	K	C	K	V	N	N	K	D	L	P	A	P	I	E	R	T	I	S	K	P	K	G	S	V	R	A	P	Q	V	Y	V	L	P	P	P	E	E	E	M	T	K	K	Q	V	T	L	T	C	M	V	T	D	F	M	P	E	D	I	Y	V	E	W	T	N	N	G	K	T	E	L	N	Y	K	N


401										411										421										431										441										451
T	E	P	V	L	D	S	D	G	S	Y	F	M	Y	S	K	L	R	V	E	K	K	N	W	V	E	R	N	S	Y	S	C	S	V	V	H	E	G	L	H	N	H	H	T	T	K	S	F	S	R	T	P	G

1										11										21										31										41										51										61										71										81										91
Q	V	Q	L	V	E	S	G	G	G	V	V	Q	P	G	R	S	L	R	L	S	C	A	A	S	G	F	A	F	S	S	Y	G	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	V	A	V	I	W	F	D	G	T	K	K	Y	Y	T	D	S	V	K	G	R	F	T	I	S	R	D	N	S	K	N	T	L	Y	L	Q	M	N	T	L	R	A	E	D	T	A	V	Y	Y	C	A	R	D	R
																																																																																							1

101										111										121										131										141										151										161										171										181										191
G	I	G	A	R	R	G	P	Y	Y	M	D	V	W	G	K	G	T	T	V	T	V	S	S	A	K	T	T	A	P	S	V	Y	P	L	A	P	V	C	G	D	T	T	G	S	S	V	T	L	G	C	L	V	K	G	Y	F	P	E	P	V	T	L	T	W	N	S	G	S	L	S	S	G	V	H	T	F	P	A	V	L	Q	S	D	L	Y	T	L	S	S	S	V	T	V	T	S	S	T	W	P


201										211										221										231										241										251										261										271										281										291
S	Q	S	I	T	C	N	V	A	H	P	A	S	S	T	K	V	D	K	K	I	E	P	R	G	P	T	I	K	P	C	P	P	C	K	C	P	A	P	N	L	L	G	G	P	S	V	F	I	F	P	P	K	I	K	D	V	L	M	I	S	L	S	P	I	V	T	C	V	V	V	D	V	S	E	D	D	P	D	V	Q	I	S	W	F	V	N	N	V	E	V	H	T	A	Q	T	Q	T	H	R


301										311										321										331										341										351										361										371										381										391
E	D	Y	N	S	T	L	R	V	V	S	A	L	P	I	Q	H	Q	D	W	M	S	G	K	E	F	K	C	K	V	N	N	K	D	L	P	A	P	I	E	R	T	I	S	K	P	K	G	S	V	R	A	P	Q	V	Y	V	L	P	P	P	E	E	E	M	T	K	K	Q	V	T	L	T	C	M	V	T	D	F	M	P	E	D	I	Y	V	E	W	T	N	N	G	K	T	E	L	N	Y	K	N


401										411										421										431										441										451
T	E	P	V	L	D	S	D	G	S	Y	F	M	Y	S	K	L	R	V	E	K	K	N	W	V	E	R	N	S	Y	S	C	S	V	V	H	E	G	L	H	N	H	H	T	T	K	S	F	S	R	T	P	G