| | | | | | | |
| System taken down to clean quadrupole. | 2022-04-01 | | <924> | Figure 2 System Suitability | 2024-04-09 | 2024-04-09 |
| Replaced Pump S buffer. | 2022-03-21 | | <923> | Figure 2 System Suitability | 2024-04-09 | 2024-04-09 |
| LC issue - speculate related to Pump S buffer? | 2022-03-21 | | <923> | Figure 2 System Suitability | 2024-04-09 | 2024-04-09 |
| New operator. 1 ug injection of plasma-derived particles. | 2022-03-13 | | Technician Change | Figure 2 System Suitability | 2024-04-09 | 2024-04-09 |
| Swapped to PepSep column. | 2022-03-13 | | <925> | Figure 2 System Suitability | 2024-04-09 | 2024-04-09 |
| Clean quadrupole and hexapole cartridge | 2021-05-29 | | Instrumentation Change | Impact-II weekly QC | 2021-05-31 | 2021-05-31 |
| Cleaning of glass capillary | 2021-05-28 | | Instrumentation Change | Impact-II weekly QC | 2021-05-28 | 2021-05-28 |
| new PicoTip emitter (New Objective, Stock #: FS360-50-15-D-20, DOM: 12-04-2018, Coating: 1P-4P, Tip: 15+/-1um) | 2021-04-15 | | Instrumentation Change | Impact-II weekly QC | 2021-04-16 | 2021-04-16 |
| new PicoTip emitter (New Objective, Stock #: FS360-50-15-D-20, DOM: 12-04-2018, Coating: 1P-4P, Tip: 15+/-1um) | 2020-10-27 | | Instrumentation Change | Impact-II weekly QC | 2020-11-06 | 2020-11-06 |
| Binary pump repair (Halani); new trapping column Symmetry C18 (PN: 186006526; SN: 03033707416509); new nanoT; new separating column Peptide BEH C18 (PN: 186003545; SN: 02833626616217); new ZDV connection (Waters Nr. 289000439) | 2020-10-01 | | Instrumentation Change | Impact-II weekly QC | 2020-10-03 | 2020-10-06 |
| Coll.RF 762 -> 1975; F3L5 -10 -> 0; Corr.Lens 6100 -> 6300; Push pull 1860 -> 1850; Corr.Fill 60 -> 64; Corr.Extr. 975 -> 995; F3L4 3.9 -> 3.0 | 2020-09-23 | | Instrumentation Change | Impact-II weekly QC | 2020-09-23 | 2020-09-24 |
| Clean Hexapole cartridge, New default instrument parameter tuning: F3L5 0.0 -> -10.0V, F2 350 -> 300, Hex 400 -> 300, Coll.RF 2000 -> 762, Push Pull 1850 -> 1860, Corr.Extr. 995 -> 975, Corr.Lens 6300 -> 6100, Corr.Fill 64.4 -> 60.0, F1L2: 32.4 -> 32.0, Decel. 878.1 -> 877.0, F3L4 3.0 -> 3.9 , F2L1 -16.8 -> -15.8, TOFdetect.Autotune 2287 -> 2267; change picoemitter tip | 2020-09-17 | | Instrumentation Change | Impact-II weekly QC | 2020-09-21 | 2020-09-21 |
| Instrument tuning (voltages): Pulser Push Pull 1850 -> 1850, F3L3 -77.8 -> -86.0, F2L3 27.8 -> 25.7, Reflector 2495 -> 2495, Corr.Fill 62.8 -> 64.4, Corr.Extr. 995 -> 995, Corr.Lens 6400 -> 6300, TOFdetect.Autotune 2237.8 -> 2287, F1 300 - > 150, F2 350 -> 200, H 400 -> 300 | 2020-09-02 | | Instrumentation Change | Impact-II weekly QC | 2020-09-02 | 2020-09-02 |
| Cleaning of glass capillary | 2020-08-28 | | Instrumentation Change | Impact-II weekly QC | 2020-08-28 | 2020-08-28 |
| PicoTip emitter (New Objective, Stock #: FS360-50-15-D-20, DOM: 12-04-2018, Coating: 1P-4P, Tip: 15+/-1um) | 2020-08-27 | | Instrumentation Change | Impact-II weekly QC | 2020-08-28 | 2020-08-28 |
| Repair of binary pump (BSM), change of some solvent lines; annual PM SM and BSM; | 2020-08-26 | | Instrumentation Change | Impact-II weekly QC | 2020-08-28 | 2020-08-28 |
| PicoTip emitter (New Objective, Stock #: FS360-50-15-D-20, DOM: 12-04-2018, Coating: 1P-4P, Tip: 15+/-1um) | 2020-07-15 | | Instrumentation Change | Impact-II weekly QC | 2020-07-16 | 2020-07-30 |
| PicoTip emitter (New Objective, Stock #: FS360-50-15-D-20, DOM: 12-04-2018, Coating: 1P-4P, Tip: 15+/-1um) | 2020-06-12 | | Instrumentation Change | Impact-II weekly QC | 2020-06-17 | 2020-07-25 |
| Glass capillary (Bruker), Serial #: 11483-1-28 (Mfg part 38821, RGP T 6.48- ,5/Date 20-Dec-19) | 2020-06-12 | | Instrumentation Change | Impact-II weekly QC | 2020-06-17 | 2020-07-25 |
| Instrument tuning (voltages) | 2020-06-12 | | Instrumentation Change | Impact-II weekly QC | 2020-06-17 | 2020-06-17 |
| Trap column (Waters Symmetry C18, 10k 2G V/V, 100A, 5 um, 180um x 20 mm, Product #: 186006526, Serial #: 03033704716505) | 2020-06-10 | | Instrumentation Change | Impact-II weekly QC | 2020-06-17 | 2020-07-25 |
| Separation column (Waters BEH C18 10k psi, 130A, 1.7 um, 75 um x 250 mm, Product #: 186003545, Serial #: 02833704026201) | 2020-06-10 | | Instrumentation Change | Impact-II weekly QC | 2020-06-17 | 2020-07-25 |
| Clean Hexapole cartridge | 2020-06-10 | | Instrumentation Change | Impact-II weekly QC | 2020-06-17 | 2020-06-17 |
| Clean Quadrupole | 2020-06-10 | | Instrumentation Change | Impact-II weekly QC | 2020-06-17 | 2020-06-17 |
| Clean Collision cell | 2020-06-10 | | Instrumentation Change | Impact-II weekly QC | 2020-06-17 | 2020-06-17 |
| 0.1% Formic acid (ThermoFisher BP1215-500, UN1779) in water (ThermoFisher Optima-LCMS, W6-4, Lot 202363) | 2020-06-10 | | Reagent Change | Impact-II weekly QC | 2020-07-25 | 2020-07-25 |
| Acetonitrile (ThermoFisher Optima-LCMS, A955-4, Lot 191742) | 2020-06-10 | | Reagent Change | Impact-II weekly QC | 2020-07-25 | 2020-07-25 |
| ESI-L Low concentration tuning mix (Agilent Technologies,Part #: 01969-85000, Lot #: 0006457849, expires 30-Apr-2021) | 2020-06-10 | | Reagent Change | Impact-II weekly QC | 2020-07-25 | 2020-07-25 |
| Sample vial empty. Peak areas go down, no change in retention times | 2018-10-22 | | <325> | Lindsay's Real World System Suitability | 2018-10-25 | 2018-10-25 |
| Instrument calibrated | 2018-10-12 | | Instrumentation Change | Lindsay's Real World System Suitability | 2018-10-25 | 2022-07-14 |
| LKP got on the instrument | 2018-10-11 | | Technician Change | Lindsay's Real World System Suitability | 2018-10-25 | 2018-10-25 |
| Column clogged | 2018-08-21 | | <324> | Lindsay's Real World System Suitability | 2018-10-25 | 2018-12-20 |
| Column clogged | 2018-08-16 | | <324> | Lindsay's Real World System Suitability | 2018-10-25 | 2019-03-19 |
| LKP got on the instrument | 2018-08-16 | | Technician Change | Lindsay's Real World System Suitability | 2018-10-25 | 2018-10-25 |
| Instrument calibrated | 2018-08-16 | | Instrumentation Change | Lindsay's Real World System Suitability | 2018-10-25 | 2018-10-25 |
| LKP got on the instrument | 2018-01-12 | | Technician Change | Lindsay's Real World System Suitability | 2018-10-25 | 2018-10-25 |
| LKP got on the instrument | 2017-11-02 | | Technician Change | Lindsay's Real World System Suitability | 2018-10-25 | 2018-10-25 |
| Cory ran QC samples | 2013-08-22 | | Technician Change | System Suitability | 2016-06-04 | 2016-06-04 |
| Replaced column | 2013-08-21 | | Instrumentation Change | System Suitability | 2016-02-04 | 2016-03-08 |
| New reagent lot | 2013-08-15 | | Reagent Change | System Suitability | 2016-06-04 | 2016-06-04 |
| Power loss | 2013-08-12 | | Instrumentation Change | System Suitability | 2016-06-04 | 2016-06-04 |
| Empty run SSS_run_139 | 2011-09-23 | | <237> | Site 54 | 2017-06-27 | 2017-06-27 |
| MS cleaning | 2011-09-11 | | Instrumentation Change | Site 56A | 2017-06-27 | 2017-06-27 |