E126_MP_EXP1_RevCurves_20141215_UPLOAD DOC_2015-06-08_14-46-49.sky.zip

ResponseCurve
 
54 proteins, 130 peptides, 260 precursors, 1,658 transitions  -  30 replicates  -  Skyline-daily (64-bit) 3.1.1.7490
Protein Note/Annotations
 
>sp|Q13085|ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA PE=1 SV=2 
Peptide Note/Annotations
Precursor Note/Annotations
SSMSGLHLVK
PeptideConcentration: 19.3
PeptideConcentrationIS: 2.9
01137.5253 
SSMSGLHLVK
light2+569.76991137.5253632.610672.6532
SSMSGLHLVK
PeptideConcentration: 19.3
PeptideConcentrationIS: 2.9
01137.5253 
SSMSGLHLVK
heavy2+573.77701145.5395632.610672.6532
>sp|P31749|AKT1_HUMAN RAC-alpha serine/threonine-protein kinase OS=Homo sapiens GN=AKT1 PE=1 SV=2 
Peptide Note/Annotations
Precursor Note/Annotations
FFAGIVWQHVYEK
PeptideConcentration: 11.4
PeptideConcentrationIS: 1.6
01622.8245 
FFAGIVWQHVYEK
light3+541.94881622.8245628.871870.6251
FFAGIVWQHVYEK
PeptideConcentration: 11.4
PeptideConcentrationIS: 1.6
01622.8245 
FFAGIVWQHVYEK
heavy3+544.62021630.8387628.871870.6251
QEEEEMDFR
PeptideConcentration: 18.6
PeptideConcentrationIS: 3.2
01211.4765 
QEEEEMDFR
light2+606.74551211.4765434.921675.3487
QEEEEMDFR
PeptideConcentration: 18.6
PeptideConcentrationIS: 3.2
01211.4765 
QEEEEMDFR
heavy2+611.74961221.4847434.921675.3487
>sp|Q96B36|AKTS1_HUMAN Proline-rich AKT1 substrate 1 OS=Homo sapiens GN=AKT1S1 PE=1 SV=1 
Peptide Note/Annotations
Precursor Note/Annotations
CLHDIALAHR
PeptideConcentration: 6.2
PeptideConcentrationIS: 1.6
01204.6135 
CLHDIALAHR
light3+402.54511204.6135620.159160.4625
CLHDIALAHR
PeptideConcentration: 6.2
PeptideConcentrationIS: 1.6
01204.6135 
CLHDIALAHR
heavy3+405.88121214.6218620.159160.4625
LNTSDFQK
PeptideConcentration: 13.7
PeptideConcentrationIS: 4.3
01031.4325 
LNTSDFQK
light2+516.72351031.4325229.295268.7861
LNTSDFQK
PeptideConcentration: 13.7
PeptideConcentrationIS: 4.3
01031.4325 
LNTSDFQK
heavy2+520.73061039.4467229.295268.7861
SLPVSVPVWGFK
PeptideConcentration: 17.2
PeptideConcentrationIS: 3.3
01314.7336 
SLPVSVPVWGFK
light2+658.37411314.7336638.148479.1125
SLPVSVPVWGFK
PeptideConcentration: 17.2
PeptideConcentrationIS: 3.3
01314.7336 
SLPVSVPVWGFK
heavy2+662.38121322.7478638.148479.1125
>sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kinase OS=Homo sapiens GN=AKT2 PE=1 SV=2 
Peptide Note/Annotations
Precursor Note/Annotations
APGEDPMDYK
PeptideConcentration: 17.4
PeptideConcentrationIS: 2.5
01121.4699 
APGEDPMDYK
light2+561.74221121.4699632.108972.0680
APGEDPMDYK
PeptideConcentration: 17.4
PeptideConcentrationIS: 2.5
01121.4699 
APGEDPMDYK
heavy2+565.74931129.4841632.108972.0680
YDSLGLLELDQR
PeptideConcentration: 9.8
PeptideConcentrationIS: 1.2
01420.7198 
YDSLGLLELDQR
light2+711.36721420.7198841.460482.9757
YDSLGLLELDQR
PeptideConcentration: 9.8
PeptideConcentrationIS: 1.2
01420.7198 
YDSLGLLELDQR
heavy2+716.37131430.7281841.460482.9757
>sp|Q13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 OS=Homo sapiens GN=BIRC2 PE=1 SV=2 
Peptide Note/Annotations
Precursor Note/Annotations
AVEDISSSR
PeptideConcentration: 6.4
PeptideConcentrationIS: 0.9
0962.4669 
AVEDISSSR
light2+482.2407962.4669427.140066.2723
AVEDISSSR
PeptideConcentration: 6.4
PeptideConcentrationIS: 0.9
0962.4669 
AVEDISSSR
heavy2+487.2449972.4752427.140066.2723
LGDSPIQK
PeptideConcentration: 16.0
PeptideConcentrationIS: 1.7
0856.4654 
LGDSPIQK
light2+429.2400856.4654723.827562.4086
LGDSPIQK
PeptideConcentration: 16.0
PeptideConcentrationIS: 1.7
0856.4654 
LGDSPIQK
heavy2+433.2471864.4796723.827562.4086
>sp|Q92851|CASPA_HUMAN Caspase-10 OS=Homo sapiens GN=CASP10 PE=1 SV=3 
Peptide Note/Annotations
Precursor Note/Annotations
HEDILSILTAVNDDVSR
PeptideConcentration: 9.8
PeptideConcentrationIS: 0.9
01895.9589 
HEDILSILTAVNDDVSR
light3+632.99361895.9589634.562177.2622
HEDILSILTAVNDDVSR
PeptideConcentration: 9.8
PeptideConcentrationIS: 0.9
01895.9589 
HEDILSILTAVNDDVSR
heavy3+636.32971905.9671634.562177.2622
LLIIDSNLGVQDVENLK
PeptideConcentration: 12.5
PeptideConcentrationIS: 0.7
01882.0411 
LLIIDSNLGVQDVENLK
light2+942.02781882.0411255.876799.7908
LLIIDSNLGVQDVENLK
PeptideConcentration: 12.5
PeptideConcentrationIS: 0.7
01882.0411 
LLIIDSNLGVQDVENLK
heavy2+946.03491890.0553255.876799.7908
>sp|Q14790|CASP8_HUMAN Caspase-8 OS=Homo sapiens GN=CASP8 PE=1 SV=1 
Peptide Note/Annotations
Precursor Note/Annotations
FLLQEEISK
PeptideConcentration: 19.6
PeptideConcentrationIS: 1.5
01105.6019 
FLLQEEISK
light2+553.80821105.6019631.613071.4896
FLLQEEISK
PeptideConcentration: 19.6
PeptideConcentrationIS: 1.5
01105.6019 
FLLQEEISK
heavy2+557.81531113.6161631.613071.4896
FLSLDYIPQR
PeptideConcentration: 12.8
PeptideConcentrationIS: 1.5
01250.6659 
FLSLDYIPQR
light2+626.34021250.6659736.146376.7772
FLSLDYIPQR
PeptideConcentration: 12.8
PeptideConcentrationIS: 1.5
01250.6659 
FLSLDYIPQR
heavy2+631.34441260.6742736.146376.7772
>sp|P06493|CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo sapiens GN=CDK1 PE=1 SV=3 
Peptide Note/Annotations
Precursor Note/Annotations
IGEGTYGVVYK
PeptideConcentration: 28.9
PeptideConcentrationIS: 5.0
01264.5741 
IGEGTYGVVYK
light2+633.29431264.5741236.580977.2842
IGEGTYGVVYK
PeptideConcentration: 28.9
PeptideConcentrationIS: 5.0
01264.5741 
IGEGTYGVVYK
heavy2+637.30141272.5883236.580977.2842
IGEGTYGVVYK
PeptideConcentration: 21.5
PeptideConcentrationIS: 4.1
01264.5741 
IGEGTYGVVYK
light2+633.29431264.5741636.580977.2842
IGEGTYGVVYK
PeptideConcentration: 21.5
PeptideConcentrationIS: 4.1
01264.5741 
IGEGTYGVVYK
heavy2+637.30141272.5883636.580977.2842
IGEGTYGVVYK
PeptideConcentration: 26.1
PeptideConcentrationIS: 4.3
01184.6077 
IGEGTYGVVYK
light2+593.31111184.6077834.081974.3694
IGEGTYGVVYK
PeptideConcentration: 26.1
PeptideConcentrationIS: 4.3
01184.6077 
IGEGTYGVVYK
heavy2+597.31821192.6219834.081974.3694
VYTHEVVTLWYR
PeptideConcentration: 22.0
PeptideConcentrationIS: 4.0
01644.7701 
VYTHEVVTLWYR
light3+549.26401644.7701129.329071.1583
VYTHEVVTLWYR
PeptideConcentration: 22.0
PeptideConcentrationIS: 4.0
01644.7701 
VYTHEVVTLWYR
heavy3+552.60011654.7784129.329071.1583
VYTHEVVTLWYR
PeptideConcentration: 22.9
PeptideConcentrationIS: 4.3
01644.7701 
VYTHEVVTLWYR
light3+549.26401644.7701129.329071.1583
VYTHEVVTLWYR
PeptideConcentration: 22.9
PeptideConcentrationIS: 4.3
01644.7701 
VYTHEVVTLWYR
heavy3+552.60011654.7784129.329071.1583
VYTHEVVTLWYR
PeptideConcentration: 21.6
PeptideConcentrationIS: 3.5
01564.8038 
VYTHEVVTLWYR
light3+522.60851564.8038627.663069.2152
VYTHEVVTLWYR
PeptideConcentration: 21.6
PeptideConcentrationIS: 3.5
01564.8038 
VYTHEVVTLWYR
heavy3+525.94461574.8121627.663069.2152
>sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 
Peptide Note/Annotations
Precursor Note/Annotations
GSHQISLDNPDYQQDFFPK
PeptideConcentration: 12.6
PeptideConcentrationIS: 5.3
02314.9896 
GSHQISLDNPDYQQDFFPK
light3+772.67052314.9896843.291987.4447
GSHQISLDNPDYQQDFFPK
PeptideConcentration: 12.6
PeptideConcentrationIS: 5.3
02314.9896 
GSHQISLDNPDYQQDFFPK
heavy3+775.34192323.0038843.291987.4447
MHLPSPTDSNFYR
PeptideConcentration: 12.6
PeptideConcentrationIS: 7.3
01643.6803 
MHLPSPTDSNFYR
light3+548.90071643.6803229.306371.1319
MHLPSPTDSNFYR
PeptideConcentration: 12.6
PeptideConcentrationIS: 7.3
01643.6803 
MHLPSPTDSNFYR
heavy3+552.23681653.6886229.306371.1319
>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B PE=1 SV=2 
Peptide Note/Annotations
Precursor Note/Annotations
TTSFAESCKPVQQPSAFGSMK
PeptideConcentration: 24.8
PeptideConcentrationIS: 4.8
02367.0276 
TTSFAESCKPVQQPSAFGSMK
light3+790.01652367.0276744.376088.7092
TTSFAESCKPVQQPSAFGSMK
PeptideConcentration: 24.8
PeptideConcentrationIS: 4.8
02367.0276 
TTSFAESCKPVQQPSAFGSMK
heavy3+792.68792375.0418744.376088.7092